Breaking down the 2025 draft picks for the San Francisco 49ers, interior defensive linemen Alfred Collins and CJ West stand out. Collins, at 6'6" and 332 lbs, brings immense size but is noted for needing improvement in pass-rushing skills. His ability to impact run defense is promising, though concerns linger about his overall agility. West, drafted later, complements Collins as a stout nose tackle with effective leverage and the potential to push the pocket, though both players are seen primarily as run stoppers. The 49ers are looking to enhance their defensive line and improve their run defense with these selections, aiming to recreate the dominant front that characterized their earlier success.